What you should know about Iovera Treatment
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What you should know about Iovera Treatment


Surgery may be in your future, but a painful recovery doesn’t have to be. Physicians can help pave the way for a smooth recovery before a patient even gets to the hospital.

The iovera° treatment is a clinically proven, non-opioid, long-lasting pain management solution that uses the body’s natural response to cold to relieve pain. It can be performed prior to knee surgery to help reduce pain after surgery.

The iovera° treatment is based upon the well-established principles of cryoneurolysis. The iovera° system uses an innovative process to form a targeted cold zone surrounding peripheral nerve tissue to immediately block the nerve from sending pain signals. The system is specifically designed to create a temporary, reversible nerve block through a process called Wallerian degeneration that is followed by predictable regeneration of the nerves. The treatment does not include injection of any substance – drugs, opioids or narcotics. The effect of this treatment is immediate and can last up to 90 days. It is important to note that iovera° treatment does not treat the underlying cause of the pain. Timely remediation is necessary to address and treat the cause of pain.

With over 15,000 patient treatments performed to date, iovera° therapy represents a promising option for physicians to manage their patients’ pain.

Clinical results comparing patients who were treated with iovera° technology five days prior to total knee replacement (TKA) surgery to patients who did not receive this therapy, have shown that the iovera° therapy group:

• requested fewer opioids than the control group, while reporting similar function and pain scores

• experienced less stiffness at six and 12 weeks post-surgery

• experienced less knee pain at six and 12 weeks post-surgery

The use and abuse of opioids is a trending concern throughout our country. It is important to explore every non-opioid treatment available, in conjunction with an appropriate amount of opioid, in order to maximize the recovery and rehabilitation of surgical patients. Iovera has given us another non-opioid option to treat pain.

Chad Miller is the director of Anesthesia at Columbus Community Hospital.


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